What is the difference between capillary and venous blood glucose




















Abstract Background: Poisoning is one of the most common medical presentations in a hospital. Results: The mean of capillary blood glucose was Conclusion: Using venous blood sample and measuring the glucose level in it by glucometer is an acceptable and advisable method, and capillary blood glucose measurement by using glucometer is not recommended for patients in coma.

Keywords: Blood glucose monitoring, glucometry, poisoned patients. Glucose measurements Blood samples were obtained immediately after ABC. Open in a separate window. Figure 1. Figure 2. Figure 3. Figure 4. Table 2 Mean and standard deviation and range of blood glucose with the three methods. Comparison between arterial and capillary blood glucose monitoring in patients with shock.

Eur J Intern Med. Marghli S, Elatrous S. Bedside capillary blood glucose measurements in critically ill patients: Influence of catecholamine therapy. Diabetes Res Cline Pract. Accuracy of bedside glucometry in critically ill patients: Influence of clinical characteristics and perfusion index. Mayo Clin Proc. Comparison of capillary and venous Glucose measurements in healthy volunteers. Prehosp Emerg Care. Capillary and Venous blood Glucose measurements using a direct glucose sensing meter.

Diabet Med. Capillary versus venous bedside blood glucose estimation. Emerg Med. Is there a relationship between admission blood glucose level following acute poisoning and clinical outcome.? Arch Med Sci. Validation of capillary glucose measurements to detect glucose intolerance or type 2 diabetes mellitus in the general population. Clin Chim Acta. Poisoning severity score. Grading of acute poisoning. J Toxicol Clin Toxicol. Ousman Y. Hyperglycemia in the hospitalized patient.

Clin Diabetes. Relationships of glucose concentrations in capillary whole blood, venous whole blood and venous plasma. Discrepancies between capillary glucose measurements and traditional laboratory assessments in both shock and non-shock states after trauma.

J Surg Res. Support Center Support Center. External link. Please review our privacy policy. Implementation will do much to harmonize glucose testing and should prevent many of the most serious errors of interpretation. Investigation of discordance between glucose results obtained at the point of care with results obtained in the central laboratory must take account of sample type, detail of measuring systems, characteristics of the patient and possible ways in which each of these three elements might interact to affect glucose result.

May contain information that is not supported by performance and intended use claims of Radiometer's products. See also Legal info. Radiometer and acutecaretesting. Printed from acutecaretesting. January Measurement of circulating glucose: The problem of inconsistent sample and methodology. THE SAMPLE Glucose concentration might be measured using a whole blood sample either venous, arterial or capillary ; or a plasma sample recovered after centrifugation of anticoagulated whole blood either venous, arterial or capillary ; or a serum sample recovered after centrifugation of non-anticoagulated whole blood either venous, arterial or capillary.

Whole blood glucose concentration is determined by three parameters: plasma glucose concentration, pl gluc; red cell glucose concentration, rc gluc approximately Difference between venous plasma and venous serum glucose concentration The glucose concentration of venous plasma and venous serum should theoretically be the same. FIGURE 1: Glucose concentration is sample dependent adapted from ref 4 Note the the difference between capillary blood glucose and venous sample types depends on the time since last meal.

Venous plasma - the reference sample Of all the clinical contexts in which glucose is measured, diagnosis of diabetes is the one that demands greatest accuracy and precision. Hexokinase methods In the central laboratory, glucose-measuring platforms on automated analyzers are most frequently based on the enzyme hexokinase [16]. FIGURE 2a: Glucose measurement - hexokinase Glucose oxidase - photometric and amperometric Both laboratory-based and point-of-care glucose measuring systems utilize the enzyme glucose oxidase.

FIGURE 2b: Glucose measurement - glucose oxidase The consumption of oxygen or production of hydrogen peroxide that results from glucose oxidase action allows amperometric measurement of glucose. Glucose dehydrogenase - the HemoCue analyzer Glucose measuring systems based on glucose dehydrogenase are fewer in number than those based on glucose oxidase or hexokinase but the HemoCue glucose analyzer is an example of one that does. Ravel R. Tests for Diabetes and hypoglycemia.

In: Clinical laboratory Medicine 6th Ed. St Louis, Missouri: Mosby, Faye S, Payne R. Rapid Measurement of serum water to assess pseudohyponatremia. Clin Chem ; Red cell electrolytes in patients with edema. J Lab Clin Med ; Relationship of glucose concentration in capillary whole blood, venous whole blood and venous plasma. Clin Chim Acta ; Comparability of blood glucose concentrations measured in different sampling systems for detecting glucose intolerance.

Effectiveness of sodium fluoride as a preservative of glucose in blood. Glycolysis inhibitors negatively bias blood glucose measurements: potential impact on the reported prevalence of diabetes mellitus. J Clin Pathol ; Guidelines and recommendations for laboratory analysis and management of diabetes mellitus. Diagnosis and classification of diabetes. Diabetes Care ; S Approved IFCC recommendation on reporting results for blood glucose abbreviated. Steffes M, Sacks D. Measurement of circulating glucose concentrations: The time is now for consistency among methods and types of samples.

Approved IFCC recommendation on reporting results for blood glucose. Clin Chem Lab Med ; Fogh-Anderson N. Point of Care ; Sluss P. Bedside blood glucose testing systems: current technology Point of Care ; 5: Twomey P. Biosensors in clinical chemistry. Clin Cim Acta ; Direct reading glucose electrodes detect molality of glucose in plasma and whole blood.

Fogh-Anderson N, Orazio P. Proposal for standardizing direct-reading biosensors for blood glucose. Clin Chem ; Weiner K. An assessment of the effect of haematocrit on the HemoCue blood glucose analyzer. Ann Clin Biochem ; Effects of different hematocrit levels on glucose measurements with hand held meters for point of care testing. Arch Pathol Lab Med ; Variations in sample pH and pO2 affect ExachTech meter glucose measurements. Diabetic Med ; Finger-stick glucose determination in shock.

It is well established that the education and training of glucometer operators is important to obtain accurate results. The training status of all glucometer operators included healthcare providers and family members, but details remained unknown. Raine et al. Significant insulin dose errors may occur if blood glucose results are obtained from miscoded meters. Comparison of photometric venous and glucometric capillary glucose estimations resulted in a mean difference of 0.

Capillary versus venous bedside blood glucose estimations. Emerg Med J. Clinical impact of prandial state, exercise, and site preparation on the equivalence of alternativesite blood glucose testing. Clinical impact of prandial state, exercise, and site preparation on the equivalence of alternativesite blood glucose testing Diabetes Care.

Other than various sample sites, factors that may contribute to this significant difference include hematocrit and pH of blood, drugs, triglycerides, and bilirubin [ 10 Narendra Kotwal, Aditi Pandit. Variability of capillary blood glucose monitoring measured on home glucose monitoring devices. Indian J Endocrinol Metab. The same was reported by Funk et al. Yang et al. A comparison between venous and finger-prick blood sampling on values of blood glucose.

Similar findings were reported in the present study, which verified the results by Yang et al. The correlation coefficients i.

Variability of point-of-care testing blood glucometers versus the laboratory reference method in a tertiary teaching hospital. Asian Biomed. Variability of point-of-care testing blood glucometers versus the laboratory reference method in a tertiary teaching hospital Asian Biomed.

A positive correlation coefficient showed strong association between capillary and venous glucose measurements including large percentage of illiterates. Self monitoring of blood glucose: the use of the first or the second drop of blood.



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